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Nanomedicines Characterization Core Facility  implements the CNDD mission of accelerating translation of new molecular-entity discoveries into human clinical trials through comprehensive characterization of novel nanomedicines. NCore is an open resource, which functions on a fee for service basis. Our services are organized into three independent blocks:

  1. Physicochemical Assays
  2. Comprehensive Physicochemical Characterization Studies
  3. Bioassays Characterization Package Services

Physicochemical characterization (PC) of nanomaterials offers a comprehensive body of information that can be used to predict behavior of the nanomaterials in biological environments both in vitro and in vivo. This information is essential in order to exercise tight control over inter-batch variations and maintain reproducibility of nanomaterials critical for their applications. The CNDD laboratories have state-of-the-art equipment and comprehensive expertise to perform a battery of PC studies.  NCore offers PC of various classes of nanomaterials such as:

  • Polymer conjugates
  • Polymeric micelles
  • Liposomes
  • Nanogels
  • Polyion complexes of small drugs and biomacromolecules (proteins, DNA, and RNA)
  • Inorganic/metal nanoparticles
  • Bio-derived nanoparticles such as exosomes with protein and nucleic acid cargo

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