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Nanomedicines Characterization Core Facility is part of the UNC Center for Nanotechnology in Drug Delivery (CNDD).

Nanoparticles fabrication:

Exosomes isolation and characterization:

  • Exosomes isolation from cells media/tissues (precipitation, ultracentrifugation, size exclusion)
  • Exosomal markers analysis (western blot, Exo-Check™ Exosome Antibody Array), Proteomics.

Analytical analysis:

In Vitro Assays:

  • Protein concentration (BCA assay).
  • Endotoxin contamination (LAL assay).
  • In vitro stability analysis.
  • In vitro drug release analysis.
  • In vitro cellular uptake, transfection and toxicity analysis.

Data analysis and presentation:

  • We offer expert opinion related to study design, sample selection/collection and storage, proposal review and development, manuscript development and review.

NCore collaborates with other Cores on UNC campus (TEM, Proteomics, Flow Cytometry, NMR etc) to facilitate comprehensive analysis of the samples.