Skip to main content

Nanoparticle Tracking Analysis

ZetaView® QUATT (Particle Metrix Inc.)

  • Instrument for measuring hydrodynamic particle size, zeta potential and concentration
  • Enhanced fluorescence measurement capability
  • Multi-wavelength F-NTA reduces total measurement time, minimizes the volume of sample required and improves experimental reproducibility

Laser wavelength: 405 nm, 488 nm, 520 nm, 640 nm

Key Applications

  • Extracellular Vesicles
  • Nanoparticles
  • SPIONs
  • Virus & Virus-Like-Particles (VLPs)
  • Quantum-dots


NanoSight NS500 (Malvern Panalytical, Ltd, UK)

  • Detailed and intuitive analysis of the size distribution and concentration
  • Visual validation of results gives extra confidence
  • Minimal sample preparation

Laser wavelength: 532 nm

Long pass fluorescent filter: 565 nm

Size range (diameter): 30 nm to 1000 nm

Concentration: 107 to 109 particles per ml

Sample volume: 20 – 100 ul

 Key applications:

  • Size distribution and polydispersity
  • Sample concentration
  • Protein aggregation studies
  • Exosomes and microvesicles (extracellular vesicles) characterization
  • Fluorescently labelled exosome and nanoparticles analysis

Dynamic Light Scattering/Zeta Potential meter

Zetasizer Nano ZS (Malvern Panalytical, Ltd, UK)

  • Simple, rapid, repeatable and non-destructive technique
  • Low volume sample measurement (for valuable proteins and biopolymer samples)
  • Size measurement at low concentrations

Light Source: 633 nm

Accuracy: Better than +/-2% on NIST traceable latex standards 0.12µm·cm/V·s for aqueous systems using NIST, SRM1980 standard reference material

Size range (diameter): 0.3 nm to 10 μm

Size range for Zeta potential: 3.8 nm to 100 μm

Key applications:

  • Proteins and polymer analysis
  • Size determination
  • Polydispersity index determination
  • Zeta potential measurements